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Professor, Genetics 

Research Interests

Key words: systems biology, signal transduction, cell fate decisions, cell cycle

We study the behavior of individual cells and try to understand how groups of cells work together to carry out emergent functions. We are especially interested in “irreversible” cell fates such as apoptosis, senescence, and differentiation. How does a given cell convert molecular signals into a permanent decision? How do groups of cells balance these decisions? We use a variety of experimental and computational approaches to investigate these questions including molecular profiling, time-lapse microscopy, computational modeling, and machine learning. Our ultimate goal is to not only understand how cells make decisions under physiological conditions, but to discover how to manipulate these choices to treat disease.

Mentor Training:

  • Faculty Mentoring Workshop for Biomedical Researchers
  • REI Racial Equity Workshop Phase 1

Training Program Affiliations:

  • Bioinformatics and Computational Biology
  • Biostatistics
  • Genetics and Molecular Biology

Publications

PubMed link

Opportunities

Graduate Students

We are accepting BBSP rotation students. If you are interested in doing a rotation in the lab, please send Jeremy an email and arrange a time to come by and discuss a potential rotation project.

Postdoctoral Positions

We are interested in attracting candidates with a strong background in molecular biology, experience with human cell culture and affinity to theory and computation. Experience with fluorescence microscopy and genome editing is a plus. In addition we are looking for candidates with a background in math, physics, or other quantitative disciplines who are interested in applying theory to systems-level questions in biology. To apply, e-mail a cover letter, CV and a list of three references to Jeremy.

Jeremy Purvis in UNC Genetics News

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Jeremy Purvis, PhD